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PRESS RELEASE | Medical Cannabis Reduces Pain, Preserves Cognition, Study Reveals

Contact:  Steven InfantiRothman Opioid FoundationSteven.Infanti@RothmanOpioid.Org


Medical Cannabis Reduces Pain, Preserves Cognition, Study Reveals


(Philadelphia, PA)--The results of a new study suggest patients with chronic pain are turning to medical cannabis to find relief and are also breaking free from traditional painkillers without sacrificing mental sharpness. 


Published this week in Cureus, the research reveals how patients with chronic musculoskeletal pain are using medical cannabis, the benefits they report, and the potential cognitive effects of long-term use. 


“Over 80 percent of patients who turned to medical cannabis found it effective for managing their pain. Many participants also noted improvements in associated symptoms such as sleep disturbances and anxiety, suggesting that cannabis may offer a broader range of relief than conventional pain medications alone,” says Dr. Mohammad Khak, co-author of the study and researcher at the Rothman Institute Foundation for Opioid Research & Education in Philadelphia, PA.


“This points to the possibility that cannabis could serve as a safer alternative or complement to standard pain management approaches, potentially helping to address the ongoing opioid crisis,” Dr. Ari Greis, senior author of the study and Board Member of the Rothman Institute Foundation for Opioid Research & Education as well as Assistant Professor of Orthopaedic Surgery at the Drexel University College of Medicine.   


Patients in the study used cannabis in a variety of forms, including oils, smoking, and vaporizing. Most sought out cannabis after conventional treatments failed to provide adequate relief, often in cases where their pain was particularly severe or persistent. 

The study also addressed concerns about the cognitive effects of long-term cannabis use. While some participants reported mild side effects, such as dry mouth and fatigue, most did not experience significant cognitive impairment. This finding suggests that, for many patients, medical cannabis can be integrated into chronic pain management without substantial risk to cognitive health.


The researchers note that while these patient-reported outcomes are encouraging, larger and more rigorous clinical trials are needed to fully establish the efficacy and safety of medical cannabis for chronic musculoskeletal pain. They also call for improved physician education and more straightforward regulatory guidelines to support the safe and effective use of cannabis in pain management.


A copy of the study, Patterns, Efficacy, and Cognitive Effects of Medical Cannabis Use in Chronic Musculoskeletal Pain Patients, is found online at


About the Rothman Institute Foundation for Opioid Research and Education.


The Rothman Opioid Foundation, for short, is a non-profit 501c3 organization dedicated to raising awareness of the ongoing opioid crisis, educating physicians and patients on safe opioid prescribing and use, respectively, and advising policymakers on sound opioid and pain management policy. Most importantly, the Rothman Opioid Foundation performs and supports the highest quality research on opioids and alternative pain modalities to yield findings that can better inform patients, physicians, and the greater healthcare community in the most evidence-based pain management strategies while working to mitigate opioid abuse and addiction. https://www.rothmanopioid.org/


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© 2021. Rothman Orthopaedic Institute Foundation for Opioid Research and Education.

The Rothman Orthopaedic Institute Foundation for Opioid Research & Education is a non-profit 501c3 organization dedicated to raising awareness of the risks and benefits of opioid, educate physician / physicians / policymakers on safe opioid use, and support research and education aimed to advance innovate pain management strategies that can decrease opioid use.

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